If you are searching for an irresistible snack or a quick bite that combines comfort food vibes with a health-conscious twist, the Cheesy Pepperoni Pizza Roll-Ups with Low-Carb Tortillas Recipe will become your new go-to favorite. These roll-ups bring together gooey mozzarella cheese, spicy pepperoni, and aromatic Italian seasoning, all wrapped in soft, low-carb tortillas that bake into golden perfection. They’re not only super flavorful but also perfect for busy days or casual gatherings when you want something satisfying without the carb overload. Trust me, this recipe is a total crowd-pleaser and a fun spin on classic pizza flavors that you can whip up in just about 30 minutes.

Ingredients You’ll Need
Getting started with the Cheesy Pepperoni Pizza Roll-Ups with Low-Carb Tortillas Recipe is a breeze because the ingredients list is refreshingly simple yet essential. Each component plays its part in delivering that perfect balance of texture, taste, and irresistible aroma that makes these roll-ups so addictive.
- 4 low-carb tortillas: These provide a tender but sturdy wrap that keeps the fillings snug while cutting down on carbs.
- 1 cup shredded mozzarella cheese: The melty, stringy goodness that gives every bite its cheesy charm.
- 15 slices pepperoni: Adds a savory, slightly spicy kick with plenty of meaty flavor.
- ½ cup pasta sauce (for dipping): A tangy companion that enhances the pizza vibe and keeps things saucy.
- 1 tsp Italian seasoning: A fragrant mix of herbs like oregano and basil that lifts the entire flavor profile.
How to Make Cheesy Pepperoni Pizza Roll-Ups with Low-Carb Tortillas Recipe
Step 1: Preheat and Prepare
Begin by warming your oven to 375°F (190°C) and lining a baking sheet with parchment paper. This simple prep ensures your roll-ups will bake evenly without sticking, setting the stage for that golden, crispy finish.
Step 2: Lay Out the Tortillas and Add Fillings
Spread one low-carb tortilla flat on your workspace. Generously sprinkle shredded mozzarella cheese across the surface, then layer on the pepperoni slices evenly. This layering is key to making sure every bite has that perfect balance of cheese and pepperoni flavor.
Step 3: Season and Roll Tightly
Sprinkle the Italian seasoning right over the toppings to infuse herbal notes throughout. Then roll the tortilla tightly from one end to the other, like wrapping a delicious cheesy gift. A snug roll helps keep everything inside while baking.
Step 4: Bake to Golden Perfection
Place the rolled tortilla seam-side down on your prepared baking sheet. Bake for 15 to 20 minutes until the roll-ups are golden brown and the cheese inside is bubbly and melted. This step transforms the soft tortilla into a crispy, irresistible crust.
Step 5: Slice and Serve
Once baked, let the roll-ups cool just enough to handle safely, then slice into pinwheels. Serve these warm alongside the pasta sauce for dipping. Each piece is packed with cheesy, pepperoni goodness that makes digging in so much fun.
How to Serve Cheesy Pepperoni Pizza Roll-Ups with Low-Carb Tortillas Recipe

Garnishes
To elevate your presentation and add a fresh touch, sprinkle some chopped fresh basil or a pinch of crushed red pepper flakes over the roll-ups before serving. A light drizzle of extra virgin olive oil can also add a beautiful shine and extra flavor dimension.
Side Dishes
These pizza roll-ups pair wonderfully with simple, crisp sides like a green salad tossed with lemon vinaigrette or roasted vegetables to add some balance to the meal. For a heartier option, a cup of warm tomato soup complements the cheesy rolls perfectly.
Creative Ways to Present
You can serve the Cheesy Pepperoni Pizza Roll-Ups with Low-Carb Tortillas Recipe on a rustic wooden board or a colorful platter to make them feel party-ready. Consider arranging the pinwheels in a circular pattern with a bowl of dipping sauce in the center for an inviting shareable appetizer setup.
Make Ahead and Storage
Storing Leftovers
If you have any leftovers, store the roll-ups in an airtight container in the refrigerator. They will stay fresh for up to 3 days, making for convenient snacks or quick lunches during the week.
Freezing
For longer storage, these roll-ups freeze beautifully. Wrap each roll tightly in plastic wrap and place in a freezer-safe bag or container. When frozen, they keep well for up to 2 months without losing flavor or texture.
Reheating
To reheat, pop the roll-ups in a preheated oven at 350°F (175°C) for about 10-15 minutes or until warmed through and crispy again. Avoid the microwave if possible to keep the tortillas from becoming soggy.
FAQs
Can I use regular tortillas instead of low-carb?
Absolutely! While low-carb tortillas keep the recipe lighter, regular tortillas work just fine and might even give a softer texture. Just be mindful of the carb content if that’s a concern for you.
Is there a vegetarian version of this recipe?
Yes, you can easily swap the pepperoni for sliced mushrooms, bell peppers, or spinach. Adding veggies keeps things flavorful and still pairs wonderfully with the cheese and Italian seasoning.
How spicy are these roll-ups?
The spice level is mild, mainly coming from the pepperoni and Italian seasoning. If you want more heat, you can add crushed red pepper flakes or spicy pepperoni to kick it up a notch.
Can I make these roll-ups ahead of time for a party?
Definitely! Prepare and assemble the roll-ups in advance, store them in the fridge unbaked, and bake right before serving. This saves time while still delivering fresh, hot appetizers.
What dipping sauces work well besides pasta sauce?
Try marinara, garlic butter dip, ranch dressing, or even a spicy sriracha mayo. Each adds a tasty twist that complements the cheesy, savory roll-ups wonderfully.
Final Thoughts
The Cheesy Pepperoni Pizza Roll-Ups with Low-Carb Tortillas Recipe is a delicious and versatile dish that’s sure to brighten your snack time or meal rotations. It’s easy to make, packed with flavor, and wonderfully adaptable for any occasion. I truly can’t recommend giving this recipe a try enough—once you do, it just might become a staple in your kitchen, just like it did in mine!
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Cheesy Pepperoni Pizza Roll-Ups with Low-Carb Tortillas Recipe
- Prep Time: 10 minutes
- Cook Time: 15-20 minutes
- Total Time: 30 minutes
- Yield: 4 servings
- Category: Appetizer
- Method: Baking
- Cuisine: Italian-American
- Diet: Low Carb
Description
These Cheesy Pepperoni Pizza Roll-Ups are a quick and delicious low-carb snack or appetizer made with low-carb tortillas, melted mozzarella cheese, and savory pepperoni slices. Perfectly seasoned with Italian herbs and baked to golden perfection, they are served with warm pasta sauce for dipping, making them an irresistible treat for any pizza lover watching their carb intake.
Ingredients
Main Ingredients
- 4 low-carb tortillas
- 1 cup shredded mozzarella cheese
- 15 slices pepperoni
- 1 tsp Italian seasoning
For Dipping
- ½ cup pasta sauce (warm)
Instructions
- Preheat Oven: Preheat your oven to 375°F (190°C) and line a baking sheet with parchment paper to prevent sticking and ensure easy cleanup.
- Assemble Roll-Ups: Lay one low-carb tortilla flat on a clean surface. Evenly sprinkle approximately a quarter cup of shredded mozzarella cheese over the tortilla, followed by about 3 to 4 slices of pepperoni. Repeat for each tortilla.
- Season and Roll: Sprinkle Italian seasoning evenly over the cheese and pepperoni on each tortilla. Starting from one edge, roll each tortilla tightly into a log shape to keep all fillings inside.
- Bake: Place each rolled tortilla seam-side down on the prepared baking sheet to prevent unraveling. Bake in the preheated oven for 15 to 20 minutes or until the tortillas are golden brown and the cheese is melted and bubbly.
- Slice and Serve: Allow the roll-ups to cool slightly to avoid burns. Using a sharp knife, slice each roll into pinwheels. Serve warm with the heated pasta sauce on the side for dipping.
Notes
- For extra flavor, add a sprinkle of crushed red pepper or garlic powder before rolling.
- Use gluten-free tortillas instead of low-carb if preferred, keeping in mind carb content may increase.
- The roll-ups can be prepared ahead of time and baked just before serving for convenience.
- Make sure to roll the tortillas tightly to prevent fillings from spilling during baking.
- Leftovers can be stored in an airtight container and reheated in the oven or air fryer for best texture.

